1.
Protein & Cell
;
(12): 240-260, 2021.
Article
in English
| WPRIM
| ID: wpr-880931
ABSTRACT
Metabolic regulation has been proven to play a critical role in T cell antitumor immunity. However, cholesterol metabolism as a key component of this regulation remains largely unexplored. Herein, we found that the low-density lipoprotein receptor (LDLR), which has been previously identified as a transporter for cholesterol, plays a pivotal role in regulating CD8